Open AccessPhenytoin in treatment of amiodarone-induced Torsades de pointes
Author(s) -
Saibal Mukhopadhyay,
Praloy Chakraborty,
Jamal Yusuf,
Anuj Goyal,
Sanjay Tyagi
Publication year - 2012
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.93866
Subject(s) - amiodarone , torsades de pointes , phenytoin , lidocaine , ventricular tachycardia , medicine , digoxin , quinidine , pharmacology , toxicity , qt interval , anesthesia , cardiology , epilepsy , atrial fibrillation , heart failure , psychiatry
Phenytoin, a class IB anti-arrhythmic agent, is considered the drug of choice for ventricular arrhythmias due to digoxin toxicity. We report successful reversion of polymorphic ventricular tachycardia secondary to amiodarone toxicity by phenytoin administration that was resistant to the conventional drugs (magnesium sulphate, lidocaine and atropine).