
Ceftriaxone-induced acute reversible encephalopathy in a patient with enteric fever
Author(s) -
Neetu Sharma,
Sandeep Batish,
Anita Gupta
Publication year - 2012
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.91884
Subject(s) - ceftriaxone , medicine , cephalosporin , encephalopathy , neurotoxicity , complication , side effect (computer science) , enteric fever , gastroenterology , anesthesia , antibiotics , toxicity , pathology , typhoid fever , computer science , microbiology and biotechnology , biology , programming language
Ceftriaxone is a commonly used, third-generation cephalosporin. Encephalopathy is a rare side effect of third- and fourth-generation cephalosporins. Renal failure and previous disease of the central nervous system predispose to this neurotoxicity. We describe a case of acute transient encephalopathy in a patient treated with ceftriaxone for enteric fever infection. Early detection of this complication is relevant given that stopping the drug usually reverts the neurological syndrome.