Open AccessThe peak bispectral index time cannot predict early phase propofol pharmacodynamics with effect site-controlled infusion algorithm
Author(s) -
Jianjun Niu,
Shanjuan Wang,
Mazhong Zhang,
Yonghua Huang,
ShiuRu Lin,
Qian Yu,
Wenyin Xu
Publication year - 2012
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.91865
Subject(s) - propofol , bispectral index , pharmacodynamics , anesthesia , medicine , algorithm , pharmacology , mathematics , pharmacokinetics
The plasma-effect site equilibration rate constant (ke0) of propofol was determined with peak bispectral index (BIS) time (T(PEAK)) in our previous study. The present study has been conducted to evaluate the ke0's performance with effect site-controlled infusion algorithm.