Open AccessSodium artesunate-induced diuresis in a patient with malaria
Author(s) -
Syed Ahmed Zaki,
Preeti Shanbag,
Vijay Lad,
Prithi Shenoy
Publication year - 2011
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.83129
Subject(s) - artesunate , diuresis , natriuresis , polyuria , medicine , discontinuation , diuretic , malaria , pharmacology , plasmodium falciparum , endocrinology , kidney , immunology , diabetes mellitus
Sodium artesunate is used in the treatment of malaria. We report a case of sodium artesunate induced diuresis and natriuresis in a patient with malaria. Following artesunate administration there was polyuria accompanied by natriuresis that was reversed after discontinuation of artesunate treatment. The diuretic effect of artesunate can modify the course of renal failure in severe malaria. Prescribers should be aware of this effect of artesunate, so that it can be used judiciously and to the advantage of patients with severe malaria.