Sodium artesunate-induced diuresis in a patient with malaria | Zendy

SyedAhmed Zaki | Zendy; Preeti Shanbag | Zendy; Vijay Lad | Zendy; Prithi Shenoy | Zendy

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Sodium artesunate-induced diuresis in a patient with malaria

Author(s) -

SyedAhmed Zaki,

Preeti Shanbag,

Vijay Lad,

Prithi Shenoy

Publication year - 2011

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.83129

Subject(s) - artesunate , diuresis , natriuresis , polyuria , medicine , discontinuation , diuretic , malaria , pharmacology , plasmodium falciparum , endocrinology , kidney , immunology , diabetes mellitus

Sodium artesunate is used in the treatment of malaria. We report a case of sodium artesunate induced diuresis and natriuresis in a patient with malaria. Following artesunate administration there was polyuria accompanied by natriuresis that was reversed after discontinuation of artesunate treatment. The diuretic effect of artesunate can modify the course of renal failure in severe malaria. Prescribers should be aware of this effect of artesunate, so that it can be used judiciously and to the advantage of patients with severe malaria.

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