Open AccessPharmacodynamic interaction study of Allium sativum (garlic) with cilostazol in patients with type II diabetes mellitus
Author(s) -
Abdul Mateen,
P. Usha Rani,
M. U. R. Naidu,
E. Chandrashekar
Publication year - 2011
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.81514
Subject(s) - cilostazol , medicine , pharmacology , placebo , pharmacodynamics , allium sativum , crossover study , aspirin , pharmacokinetics , alternative medicine , pathology , horticulture , biology
Garlic is available as an over-the-counter herbal supplement and is known to have antiplatelet properties. Because of scarcity of clinical data regarding the safety of concomitant use of garlic supplements and anticoagulants, we tried to evaluate the effects of coadministration of single and multiple doses of garlic and cilostazol on platelet aggregation.