Open AccessAcute akathisia with quetiapine: A case report and review of literature
Author(s) -
Ruchita Shah,
Sandeep Grover,
Uma Maheshwari,
Natasha Kate,
Nidhi Malhotra
Publication year - 2010
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.71896
Subject(s) - quetiapine , akathisia , quetiapine fumarate , medicine , psychology , psychiatry , schizophrenia (object oriented programming) , antipsychotic , atypical antipsychotic
Quetiapine is an atypical antipsychotic which has been shown to have greater relative affinity for 5-HT(2A) receptors than for D(2) receptors, due to which it is thought to lead to lower incidence of extrapyramidal symptoms (EPS). However, over the years literature in the form of case reports have accumulated which shows that quetiapine can lead to akathisia, especially in subjects prone to develop EPS. In this study, we report the case of a 22-year-old female who developed akathisia with quetiapine 150 mg/day, which subsided with reduction in dose. We have also reviewed the existing literature with respect to akathisia with quetiapine.