Open AccessEffective control of sickle cell disease with hydroxyurea therapy
Author(s) -
Harminder Singh,
Navin Dulhani,
Bithika Nel Kumar,
Prabhakar Singh,
Pawan Tiwari
Publication year - 2010
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.62409
Subject(s) - fetal hemoglobin , mean corpuscular volume , medicine , prospective cohort study , hemoglobin , gastroenterology , disease , pediatrics , pregnancy , fetus , genetics , biology
Hemoglobin F augmentation is another approach to treat sickle cell disease (SCD). This study evaluates the efficacy and impact of Hydroxyurea (HU) on fetal hemoglobin (HbF) and other hematological parameters, which result in decreasing the painful crisis and lower hospital admissions.