Open AccessDiagnostic dilemma in a child with congenital heart disease on sildenafil
Author(s) -
Syed Ahmed Zaki,
Deepak Dadge,
Shujaath Asif,
Preeti Shanbag
Publication year - 2009
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.55203
Subject(s) - sildenafil , medicine , discontinuation , pulmonary hypertension , heart disease , heart failure , cardiology
Sildenafil is used in infants and children mainly for the treatment of pulmonary hypertension associated with congenital heart disease. Some side-effects of sildenafil are similar to the symptoms and signs of congestive heart failure in children. We present a case of a two-month-old infant with supracardiac total anomalous venous connection and pulmonary hypertension, who presented with severe sweating and tachycardia after institution of sildenafil therapy. He improved dramatically on discontinuation of the drug.