Therapeutic insight into molsidomine, a nitric oxide donor in streptozotocin-induced diabetic nephropathy in rats | Zendy

Nathani Minaz | Zendy; Rema Razdan | Zendy

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Therapeutic insight into molsidomine, a nitric oxide donor in streptozotocin-induced diabetic nephropathy in rats

Author(s) -

Nathani Minaz,

Rema Razdan

Publication year - 2016

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.190744

Subject(s) - molsidomine , diabetic nephropathy , oxidative stress , streptozotocin , diabetes mellitus , endocrinology , malondialdehyde , medicine , nitric oxide , kidney , lipid peroxidation , renal function , nephropathy , creatinine , pharmacology , chemistry

Diabetes-induced oxidative stress and hypertension play a major role in the development of nephropathy. Hence, the present study was undertaken to evaluate the protective effects of molsidomine, a nitric oxide donor in streptozotocin (STZ)-induced diabetic nephropathy (DN) in rats.

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