Open AccessVerification of five pharmacogenomics-based warfarin administration models
Author(s) -
Meiqin Lin,
Liangping Yu,
Han-Fan Qiu,
Qi-Min Wang,
Jing Zhang,
Song Hong-tao
Publication year - 2016
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.182876
Subject(s) - vkorc1 , warfarin , dosing , pharmacogenomics , medicine , cyp2c9 , population , computer science , pharmacology , atrial fibrillation , environmental health , cytochrome p450 , metabolism
This study aims to screen and validate five individual warfarin dosing models (four Asian model algorithms, namely, Ohno, Wen, Miao, Huang, and the algorithm of International Warfarin Pharmacogenetic Consortium, namely IWPC algorithm) with the aim of evaluating their accuracy, practicality, and safety.