Open AccessThe effect of 5-aminosalicylic acid on renal ischemia-reperfusion injury in rats
Author(s) -
Shokofeh Banaei
Publication year - 2016
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.178840
Subject(s) - creatinine , medicine , nitric oxide , ischemia , pathophysiology , urinary system , reperfusion injury , antioxidant , kidney , renal ischemia , pharmacology , aminosalicylic acid , chemistry , biochemistry
Ischemia-reperfusion (IR) contributes to the development acute renal failure. Oxygen free radicals are involved in the pathophysiology of IR injury (IRI). This study was designed to investigate the effects of 5-aminosalicylic acid (5-ASA), which is known antioxidant agent, in IR-induced renal injury in rats.