A rare case of isoniazid-induced erythroderma | Zendy

Yashika Garg | Zendy; Rajeshwari Gore | Zendy; Sourabh Jain | Zendy; Arun Kumar | Zendy

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A rare case of isoniazid-induced erythroderma

Author(s) -

Yashika Garg,

Rajeshwari Gore,

Sourabh Jain,

Arun Kumar

Publication year - 2015

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.169575

Subject(s) - isoniazid , erythroderma , medicine , dermatology , tuberculosis , drug reaction , itching , adverse effect , pediatrics , drug , pharmacology , pathology

Tuberculosis is a common infectious disease in developing countries. Isoniazid is established the first-line antitubercular drug and an essential component of all antitubercular regimens. Erythroderma caused by isoniazid is an uncommon but serious adverse drug reaction. We report here a case of a 63-year-old female patient who presented with generalized redness and scaling with itching after 8 weeks of antitubercular treatment (ATT). ATT was stopped immediately, and antihistaminics were started. The patient improved over a period of 2 weeks. On sequential rechallenge, she developed similar lesions all over the body with isoniazid, hence confirming the diagnosis of isoniazid-induced erythroderma.

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