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Hypoglycemic episodes in a case of Prementrual Dysphoric Disorder on sertraline
Author(s) -
Santra Dhali R,
Parthajit Banerjee,
Santanu Munshi,
Chaudhuri Pr
Publication year - 2015
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.165193
Subject(s) - sertraline , hypoglycemia , discontinuation , sulfonylurea , medicine , fluoxetine , serotonin reuptake inhibitor , postprandial , reuptake inhibitor , psychiatry , diabetes mellitus , endocrinology , serotonin , anxiety , antidepressant , receptor
Sertraline is a selective serotonin reuptake inhibitor. It has been shown to blunt postprandial hyperglycemia in rats and to potentiate the hypoglycemic effects of sulfonylurea agents in humans. Here, we report a case of a 33-year-old nondiabetic patient with no history of glucose intolerance, who experienced multiple episodes of hypoglycemia that resolved after discontinuation of the drug. Healthcare professionals should consider sertraline among the possible causes of hypoglycemia occurring in patients receiving antidepressants.

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