Open AccessOxcarbazepine induced toxic epidermal necrolysis - a rare case report
Author(s) -
Vivek Singh Guleria,
Chetan Sharda,
Tanuja Rana,
Atul Kumar Sood
Publication year - 2015
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.161279
Subject(s) - oxcarbazepine , carbamazepine , toxic epidermal necrolysis , medicine , anticholinergic , pharmacology , anticonvulsant , epilepsy , dermatology , psychiatry
Carbamazepine, is well known to cause Stevens-Johnson syndrome and toxic epidermal necrolysis(TEN). Oxcarbazepine, a 10-keto analog of carbamazepine, is an anticholinergic, anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy. Its efficacy is similar to carbamazepine but allergic reactions and enzyme induction is low. We describe a case of oxcarbazepine induced TEN, who presented with erythematous ulcerative maculopapular rash.