Modulation of muscarinic system with serotonin-norepinephrine reuptake inhibitor antidepressant attenuates depression in mice | Zendy

Thakur Gurjeet Singh | Zendy

Open Access

Modulation of muscarinic system with serotonin-norepinephrine reuptake inhibitor antidepressant attenuates depression in mice

Author(s) -

Thakur Gurjeet Singh

Publication year - 2015

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.161260

Subject(s) - venlafaxine , tail suspension test , antidepressant , pharmacology , behavioural despair test , citalopram , muscarinic antagonist , muscarinic acetylcholine receptor , reuptake inhibitor , antagonist , monoamine neurotransmitter , venlafaxine hydrochloride , medicine , serotonin , psychology , receptor , hippocampus

Several studies suggest that muscarinic receptor antagonist scopolamine is a rapidly acting antidepressant for the treatment-resistant depression. Therefore, this study was carried out to investigate the possibility of synergistic potential of scopolamine with antidepressants for the treatment of depression without memory impairment in mice.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research