Open AccessPharmacological screening of glycine amino acid prodrug of acetaminophen
Author(s) -
Arun Parashar
Publication year - 2015
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.153431
Subject(s) - prodrug , acetaminophen , pharmacology , transaminase , antipyretic , chemistry , glycine , glutathione , analgesic , amino acid , medicine , enzyme , biochemistry
To develop an amino acid prodrug of acetaminophen with comparable therapeutic profile and less hepatotoxicity than acetaminophen.