Protective effects of amifostine on ischemia-reperfusion injury of rat kidneys | Zendy

Burhan Mayır | Zendy; AyseArducoglu Merter | Zendy; Okan Erdoğan | Zendy; Tahsin Çolak | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Protective effects of amifostine on ischemia-reperfusion injury of rat kidneys

Author(s) -

Burhan Mayır,

AyseArducoglu Merter,

Okan Erdoğan,

Tahsin Çolak

Publication year - 2015

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.153427

Subject(s) - amifostine , ischemia , medicine , malondialdehyde , blood urea nitrogen , creatinine , lipid peroxidation , pharmacology , intraperitoneal injection , reperfusion injury , urology , kidney , necrosis , glutathione , oxidative stress , anesthesia , endocrinology , toxicity , chemistry , biochemistry , enzyme

Amifostine is a drug which can eliminate free oxygen radicals that appear in the body after radiation or chemotherapeutic agent exposure. It is used to decrease the renal toxicity of cisplatin. The aim of this study was to determine the role of amifostine in warm ischemia kidney model for prevention of ischemia/reperfusion injury and also to find out the mechanism for prevention from ischemia/reperfusion injury if such an effect does exist.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research