Open AccessProtective effect of rutin on impairment of cognitive functions of due to antiepileptic drugs on zebrafish model
Author(s) -
Shagun Dubey,
Aditya Ganeshpurkar,
Divya Bansal,
Nazneen Dubey
Publication year - 2015
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.150357
Subject(s) - rutin , zebrafish , nootropic , pharmacology , medicine , adverse effect , anesthesia , chemistry , biochemistry , antioxidant , gene
The severity of adverse reactions due to antiepileptics is observed during initiation and early treatment in which impairment of cognitive effects are common. Since long time, herbal medicine is a natural remedy to treat neural symptoms. Phytochemicals have been proven to be potent neuro-protective agents. Rutin, a bioflavonoid is established to be nootropic in many studies. In this study, we aimed to determine the protective effect of rutin in zebrafish against the side effects produced by AEDs.