Open AccessEffects of combination of aliskiren and pentoxyfylline on renal function in the rat remnant kidney model of chronic renal failure
Author(s) -
Hitesh Soni,
Praful P. Patel,
Savan Patel,
Akshyaya Rath,
Aviseka Acharya,
Harshkant D. Trivedi,
Mukul Jain
Publication year - 2015
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.150351
Subject(s) - aliskiren , medicine , pentoxifylline , renal function , creatinine , kidney , kidney disease , endocrinology , tumor necrosis factor alpha , urology , combination therapy , blood pressure , renin–angiotensin system
The aim was to investigate the nephroprotective effect of combination of aliskiren (ASK), a direct renin inhibitor and pentoxifylline (PTX), inhibitor of tumor necrotic factor-alpha (TNF-alpha), in rat remnant kidney model of chronic kidney disease (CKD).