Effects of combination of aliskiren and pentoxyfylline on renal function in the rat remnant kidney model of chronic renal failure | Zendy

HiteshM Soni | Zendy; PrafulP Patel | Zendy; Savan V. Patel | Zendy; AkshyayaC Rath | Zendy; Aviseka Acharya | Zendy; HarshkantD Trivedi | Zendy; MukulR Jain | Zendy

Open Access

Effects of combination of aliskiren and pentoxyfylline on renal function in the rat remnant kidney model of chronic renal failure

Author(s) -

HiteshM Soni,

PrafulP Patel,

Savan V. Patel,

AkshyayaC Rath,

Aviseka Acharya,

HarshkantD Trivedi,

MukulR Jain

Publication year - 2015

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.150351

Subject(s) - aliskiren , medicine , pentoxifylline , renal function , creatinine , kidney , kidney disease , endocrinology , tumor necrosis factor alpha , urology , combination therapy , blood pressure , renin–angiotensin system

The aim was to investigate the nephroprotective effect of combination of aliskiren (ASK), a direct renin inhibitor and pentoxifylline (PTX), inhibitor of tumor necrotic factor-alpha (TNF-alpha), in rat remnant kidney model of chronic kidney disease (CKD).

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