Open AccessEffects of bleomycin A5 on caspase-3, P53, bcl-2 expression and telomerase activity in vascular endothelial cells
Author(s) -
Yideng Huang,
Ping Li,
Xiaoyong Tong,
Yu He,
Zhuo Yang,
Siwen Xia,
Xing-Hua Luo
Publication year - 2015
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.150337
Subject(s) - telomerase , bleomycin , apoptosis , microbiology and biotechnology , cancer research , vascular endothelial growth factor b , expression (computer science) , caspase 3 , chemistry , vascular endothelial growth factor a , vegf receptors , biology , vascular endothelial growth factor , genetics , biochemistry , computer science , programmed cell death , programming language , chemotherapy , gene
The aim of this study was to investigate the molecular mechanism of bleomycin A5 in inducing the apoptosis of human umbilical vein endothelial cells (ECV304).