Toll-like receptor 4 is involved in a protective effect of rhein on immunoglobulin A nephropathy | Zendy

Huihong Zeng | Zendy; Qingxian Zhu | Zendy; Xiaowen Chen | Zendy; Shengnan Peng | Zendy; Aixiang Fu | Zendy

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Toll-like receptor 4 is involved in a protective effect of rhein on immunoglobulin A nephropathy

Author(s) -

Huihong Zeng,

Qingxian Zhu,

Xiaowen Chen,

Shengnan Peng,

Aixiang Fu

Publication year - 2015

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.150319

Subject(s) - creatinine , nephropathy , chemistry , medicine , endocrinology , mesangial proliferative glomerulonephritis , receptor , kidney , mesangial cell , renal function , renal pathology , fibrosis , glomerulonephritis , diabetes mellitus

The objective was to investigate the protective effects of rhein on renal histology change and the effects of rhein on renal tissue toll-like receptor (TLR) 4, TLR9, transforming growth factor-β1 (TGF-β1) expression in immunoglobulin A nephropathy (IgAN) rats.

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