Open AccessToll-like receptor 4 is involved in a protective effect of rhein on immunoglobulin A nephropathy
Author(s) -
Xiaowen Chen,
Sheng-Nan Peng,
Huihong Zeng,
Aixiang Fu,
Qing Zhu
Publication year - 2015
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.150319
Subject(s) - creatinine , chemistry , nephropathy , mesangial proliferative glomerulonephritis , medicine , endocrinology , mesangial cell , renal pathology , receptor , renal function , kidney , glomerulonephritis , biology , biochemistry , diabetes mellitus
The objective was to investigate the protective effects of rhein on renal histology change and the effects of rhein on renal tissue toll-like receptor (TLR) 4, TLR9, transforming growth factor-β1 (TGF-β1) expression in immunoglobulin A nephropathy (IgAN) rats.