Effects of tanshinone IIA on the transforming growth factor β1/Smad signaling pathway in rat cardiac fibroblasts | Zendy

Jinhui Tang | Zendy; Chengye Zhan | Zendy; Daixing Zhou | Zendy; Zhihui Li | Zendy

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Effects of tanshinone IIA on the transforming growth factor β1/Smad signaling pathway in rat cardiac fibroblasts

Author(s) -

Jinhui Tang,

Chengye Zhan,

Daixing Zhou,

Zhihui Li

Publication year - 2014

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.144933

Subject(s) - smad , fibronectin , transforming growth factor , microbiology and biotechnology , western blot , signal transduction , myocardial fibrosis , intracellular , messenger rna , medicine , chemistry , endocrinology , cardiac fibrosis , immunocytochemistry , fibrosis , biology , extracellular matrix , biochemistry , gene

This study explores the mechanism of tanshinone IIA (TSN)-mediated inhibition of myocardial fibrosis by investigating the effect of TSN on transforming growth factor β1 (TGFβ1) signal transduction in rat cardiac fibroblasts (CFs).

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