Protective effect of L-arginine on gentamicin-induced nephrotoxicity in rats | Zendy

lbrahim Bashan | Zendy; Perihan Bashan | Zendy; MehmetAta Secilmis | Zendy; Erğin Singirik | Zendy

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Protective effect of L-arginine on gentamicin-induced nephrotoxicity in rats

Author(s) -

lbrahim Bashan,

Perihan Bashan,

MehmetAta Secilmis,

Erğin Singirik

Publication year - 2014

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.144915

Subject(s) - gentamicin , nephrotoxicity , creatinine , chemistry , arginine , blood urea nitrogen , urine , endocrinology , medicine , pharmacology , kidney , biochemistry , antibiotics , amino acid

L-arginine has a protective effect on gentamicin-induced renal failure and it may decrease the tubular reabsorption of another cationic substance, gentamicin due to its cationic structure. The aim of this study is to compare the possible protective effects of L-arginine and its inactive isomer D-arginine on gentamicin-induced nephrotoxicity in rats.

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