Novel 2,5-disubstituted-1,3,4-oxadiazoles as anti-inflammatory drugs | Zendy

GopalanKutty Nampurath | Zendy; Ega Durgashivaprasad | Zendy; Geetha Mathew | Zendy; Sarine Sebastian | Zendy; Sudarshan Reddy | Zendy; Jayesh Mudgal | Zendy

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Novel 2,5-disubstituted-1,3,4-oxadiazoles as anti-inflammatory drugs

Author(s) -

GopalanKutty Nampurath,

Ega Durgashivaprasad,

Geetha Mathew,

Sarine Sebastian,

Sudarshan Reddy,

Jayesh Mudgal

Publication year - 2014

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.140584

Subject(s) - in vivo , carrageenan , anti inflammatory , arthritis , pharmacology , inflammation , chemistry , nitric oxide , myeloperoxidase , edema , in vitro , adjuvant , lipopolysaccharide , oxadiazole , medicine , biochemistry , immunology , biology , organic chemistry , microbiology and biotechnology

1,3,4-oxadiazole ring is a versatile moiety with a wide range of pharmacological properties. The present work deals with the synthesis and evaluation of the anti-inflammatory activity of two novel 2,5-disubstituted-1,3,4-oxadiazoles (OSD and OPD).

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