Open AccessRandomized controlled trial of effectiveness of lafutidine versus pantoprazole in uninvestigated dyspepsia
Author(s) -
Somnath Maity,
Supriyo Choudhury,
Avijit Hazra,
Anjan Das
Publication year - 2014
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.140580
Subject(s) - pantoprazole , medicine , gastroenterology , esomeprazole , randomized controlled trial , ambulatory , omeprazole
Lafutidine is a new H2-blocker in India claimed to be more potent and effective than existing H2-blockers. Proton pump inhibitors (PPIs), by virtue of their mechanism of action, have greater efficacy than H2-blockers in gastric acid suppression. However, clinical trials comparing H2-blockers directly with PPIs are limited. We carried out a head-to-head comparison of the effectiveness of lafutidine versus the PPI pantoprazole in uninvestigated dyspepsia [CTRI/2013/12/004261].