Randomized controlled trial of effectiveness of lafutidine versus pantoprazole in uninvestigated dyspepsia | Zendy

Avijit Hazra | Zendy; Somnath Maity | Zendy; Supriyo Choudhury | Zendy; AmalKanti Das | Zendy

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Randomized controlled trial of effectiveness of lafutidine versus pantoprazole in uninvestigated dyspepsia

Author(s) -

Avijit Hazra,

Somnath Maity,

Supriyo Choudhury,

AmalKanti Das

Publication year - 2014

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.140580

Subject(s) - pantoprazole , medicine , gastroenterology , esomeprazole , randomized controlled trial , ambulatory , omeprazole

Lafutidine is a new H2-blocker in India claimed to be more potent and effective than existing H2-blockers. Proton pump inhibitors (PPIs), by virtue of their mechanism of action, have greater efficacy than H2-blockers in gastric acid suppression. However, clinical trials comparing H2-blockers directly with PPIs are limited. We carried out a head-to-head comparison of the effectiveness of lafutidine versus the PPI pantoprazole in uninvestigated dyspepsia [CTRI/2013/12/004261].

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