Open AccessAcute generalized exanthematous pustulosis induced by piroxicam: A case report
Author(s) -
Y. Chérif,
M. Jallouli,
M. Mseddi,
H. Turki,
Z. Bahloul
Publication year - 2014
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.129332
Subject(s) - acute generalized exanthematous pustulosis , piroxicam , pustulosis , medicine , dermatology , drug reaction , renal colic , antibiotics , drug , pathology , surgery , pharmacology , chemistry , biochemistry , alternative medicine , osteomyelitis , osteitis
Acute generalized exanthematous pustulosis (AGEP) is a severe adverse cutaneous reaction characterized by an acute episode of sterile pustules over erythematous-edematous skin. The main triggering drugs are antibiotics, mainly beta-lactam and macrolides. Non-steroid anti-inflammatory drugs may rarely be responsible. We describe a case of a woman with AGEP, who presented with generalized pustulosis lesions after the use of piroxicam for renal colic. The diagnosis was confirmed by the clinical and histological correlations and the dermatosis resolved after withdrawal of the drug.