A study of agreement between the Naranjo algorithm and WHO-UMC criteria for causality assessment of adverse drug reactions | Zendy

RenukaP Munshi | Zendy; MaheshN Belhekar | Zendy; SantoshR Taur | Zendy

Open Access

A study of agreement between the Naranjo algorithm and WHO-UMC criteria for causality assessment of adverse drug reactions

Author(s) -

RenukaP Munshi,

MaheshN Belhekar,

SantoshR Taur

Publication year - 2014

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.125192

Subject(s) - causality (physics) , cohen's kappa , statistic , medicine , kappa , adverse drug reaction , confidence interval , algorithm , drug reaction , pharmacovigilance , adverse effect , grading (engineering) , statistics , mathematics , drug , psychiatry , physics , quantum mechanics , geometry , civil engineering , engineering

Reliability and usefulness of various adverse drug reaction (ADR) causality assessment scales have not been fully explored. There is no universally accepted method for causality grading of ADRs. In the present study we assessed agreement between the two widely used causality assessment scales, that is, the World Health Organization-Uppsala Monitoring Center (WHO-UMC) criteria and the Naranjo algorithm.

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