Open AccessA study of agreement between the Naranjo algorithm and WHO-UMC criteria for causality assessment of adverse drug reactions
Author(s) -
Mahesh N Belhekar,
Santosh Taur,
Renuka Munshi
Publication year - 2014
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.125192
Subject(s) - causality (physics) , cohen's kappa , statistic , medicine , kappa , adverse drug reaction , confidence interval , algorithm , drug reaction , pharmacovigilance , adverse effect , grading (engineering) , statistics , mathematics , drug , psychiatry , physics , quantum mechanics , geometry , civil engineering , engineering
Reliability and usefulness of various adverse drug reaction (ADR) causality assessment scales have not been fully explored. There is no universally accepted method for causality grading of ADRs. In the present study we assessed agreement between the two widely used causality assessment scales, that is, the World Health Organization-Uppsala Monitoring Center (WHO-UMC) criteria and the Naranjo algorithm.