Open AccessComparision of uroprotective activity of reduced glutathione with Mesna in Ifosfamide induced hemorrhagic cystitis in rats
Author(s) -
Syed Amir Ali,
Sandeep Kumar Danda,
Syed Abdul Azeez Basha,
Asif Rasheed,
Osman Ahmed,
M. M. Ahmed
Publication year - 2014
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.125188
Subject(s) - mesna , ifosfamide , hemorrhagic cystitis , glutathione , medicine , group b , chemotherapy , nephrotoxicity , toxicity , pharmacology , chemistry , cyclophosphamide , cisplatin , biochemistry , enzyme
Ifosfamide (IFO) is widely used DNA-alkylating agents in cancer chemotherapy for management of solid tumors and hematological malignancies. However, hemorrhagic cystitis limits the use of IFO.