An evaluation of the protective role of α-tocopherol on free radical induced hepatotoxicity and nephrotoxicity due to chromium in rats | Zendy

AllaGopala Reddy | Zendy; Rajendran Balakrishnan | Zendy; ChitturiSree Venkat Satish Kumar | Zendy; MatukumalliUsha Rani | Zendy; MylaramKistaiah Srikanth | Zendy; Boobalan Gopu | Zendy

Open Access

An evaluation of the protective role of α-tocopherol on free radical induced hepatotoxicity and nephrotoxicity due to chromium in rats

Author(s) -

AllaGopala Reddy,

Rajendran Balakrishnan,

ChitturiSree Venkat Satish Kumar,

MatukumalliUsha Rani,

MylaramKistaiah Srikanth,

Boobalan Gopu

Publication year - 2013

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.117778

Subject(s) - malondialdehyde , lipid peroxidation , chemistry , creatinine , superoxide dismutase , nephrotoxicity , antioxidant , alanine transaminase , hexavalent chromium , glutathione , aspartate transaminase , kidney , medicine , blood urea nitrogen , biochemistry , pharmacology , alkaline phosphatase , chromium , endocrinology , enzyme , organic chemistry

To avert the health problems induced by many environmental pollutants, available antioxidants have been evaluated. The present study was aimed to investigate whether α-tocopherol could protect the hexavalent chromium (Cr VI)-induced peroxidation in the liver and kidney and to explore the underlying mechanism of the same.

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