Open AccessCeftriaxone-induced hemolysis
Author(s) -
Vivek Singh Guleria,
Nitin Sharma,
Amitabh Sagar,
Velu Nair
Publication year - 2013
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.117758
Subject(s) - ceftriaxone , hemolysis , medicine , discontinuation , cephalosporin , antibiotics , pneumonia , adverse effect , microbiology and biotechnology , biology
Immune hemolytic anemia is a rare adverse effect of ceftriaxone, a third-generation cephalosporin, which is a commonly used antibiotic. We describe a 60-years-old lady, a case of community-acquired pneumonia, who developed severe hemolysis after the first dose of ceftriaxone. Her hemoglobin dropped from 9.6 g /dl to 5.5 g /dl. However, she improved after discontinuation of the drug and blood transfusion. This report serves as a reminder to medical fraternity that life-threatening hemolysis can rarely follow administration of ceftriaxone.