Effect of sequential versus standard Helicobacter pylori eradication therapy on the associated iron deficiency anemia in children | Zendy

Hussam Murad | Zendy; HamedSaid Ali Habib | Zendy; ElamirMahmoud Amir | Zendy; TaherFawzy Halawa | Zendy

Open Access

Effect of sequential versus standard Helicobacter pylori eradication therapy on the associated iron deficiency anemia in children

Author(s) -

Hussam Murad,

HamedSaid Ali Habib,

ElamirMahmoud Amir,

TaherFawzy Halawa

Publication year - 2013

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.117757

Subject(s) - clarithromycin , tinidazole , helicobacter pylori , medicine , amoxicillin , gastroenterology , regimen , iron deficiency anemia , ferritin , gold standard (test) , urea breath test , anemia , immunology , antibiotics , helicobacter pylori infection , metronidazole , biology , microbiology and biotechnology

Helicobacter pylori infection may be associated with low iron stores and iron deficiency anemia. Eradication of infection by the standard 10-day therapy (a proton pump inhibitor [PPI], clarithromycin and amoxicillin; each given orally, twice daily) is decreasing. The sequential 10-day therapy (a PPI and amoxicillin; each given orally twice daily for 5 days; followed by a PPI, clarithromycin and tinidazole; each given orally twice daily for another 5 days) may achieve higher eradication rates. This study was designed to investigate, which eradication regimen; sequential or standard; more effectively improves the associated iron status and iron deficiency in children.

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