Open AccessAnti-inflammatory and anti-hyperalgesic effect of all-trans retinoic acid in carrageenan-induced paw edema in Wistar rats: Involvement of peroxisome proliferator-activated receptor-β/δ receptors
Author(s) -
Navneet Gill,
Krishna Reddy V. Bijjem,
Pankaj Sharma
Publication year - 2013
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.111944
Subject(s) - carrageenan , chemistry , receptor , hyperalgesia , edema , agonist , pharmacology , peroxisome proliferator activated receptor , inflammation , antagonist , retinoic acid , endocrinology , medicine , biochemistry , nociception , gene
In this study, we investigated the role of peroxisome proliferator-activated receptors (PPAR)-β/δ receptors in carrageenan-induced inflammation and in the anti-inflammatory effects of all-trans retinoic acid (ATRA).