Open AccessBiochemical and histopathological effects on liver due to acute oral toxicity of aqueous leaf extract of Ecliptaalba on female Swiss albino mice
Author(s) -
T. Singh,
Nivedita Sinha,
Anjali Singh
Publication year - 2013
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.106437
Subject(s) - toxicity , alkaline phosphatase , albumin , acute toxicity , group b , aqueous extract , oral administration , chemistry , median lethal dose , pharmacology , medicine , traditional medicine , biochemistry , enzyme
Limited data is available about the toxicity of herbal remedies used for self-medication. Since a popular medicinal plant Ecliptaalba contains various bioactive molecules, the present study aimed to observe the biochemical and histological changes in liver associated with acute oral toxicity (LD50) of aqueous extract of E. alba (L.) Hassk. in female Swiss albino mice.