Open AccessEvaluation of antiemetic effect of intravenous palonosetron versus intravenous ondansetron in laparoscopic cholecystectomy: A randomized controlled trial
Author(s) -
Baisakhi Laha,
Avijit Hazra,
Sanjib Mallick
Publication year - 2013
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.106430
Subject(s) - palonosetron , retching , ondansetron , medicine , anesthesia , antiemetic , nausea , postoperative nausea and vomiting , adverse effect , vomiting , randomized controlled trial , surgery
Incidence of postoperative nausea and vomiting (PONV), without active intervention, following laparoscopic cholecystectomy is unacceptably high. We evaluated the effectiveness of intravenous (IV) palonosetron in counteracting PONV during the first 24 hrs following laparoscopic cholecystectomy, using ondansetron as the comparator drug.