Open AccessEvaluation of antiobesity and cardioprotective effect of Gymnema sylvestre extract in murine model
Author(s) -
Vinay Kumar,
Uma Bhandari,
Chakra Dhar Tripathi,
Geetika Khanna
Publication year - 2012
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.100387
Subject(s) - medicine , endocrinology , hyperinsulinemia , gymnema sylvestre , insulin resistance , blood pressure , apolipoprotein b , diabetes mellitus , hyperlipidemia , insulin , cholesterol , traditional medicine
Obesity plays a central role in the insulin resistance syndrome, which is associated with hyperinsulinemia, hypertension, hyperlipidemia, type 2 diabetes mellitus, and an increased risk of atherosclerotic cardiovascular disease. The present study was done to assess the effect of Gymnema sylvestre extract (GSE) in the high fat diet (HFD)-induced cellular obesity and cardiac damage in Wistar rats.