Evaluation of antiobesity and cardioprotective effect of Gymnema sylvestre extract in murine model | Zendy

Uma Bhandari | Zendy; Vinay Kumar | Zendy; ChakraDhar Tripathi | Zendy; Geetika Khanna | Zendy

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Evaluation of antiobesity and cardioprotective effect of Gymnema sylvestre extract in murine model

Author(s) -

Uma Bhandari,

Vinay Kumar,

ChakraDhar Tripathi,

Geetika Khanna

Publication year - 2012

Publication title -

indian journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.286

H-Index - 59

eISSN - 1998-3751

pISSN - 0253-7613

DOI - 10.4103/0253-7613.100387

Subject(s) - medicine , endocrinology , gymnema sylvestre , hyperinsulinemia , insulin resistance , blood pressure , apolipoprotein b , diabetes mellitus , insulin , hyperlipidemia , chemistry , cholesterol , traditional medicine

Obesity plays a central role in the insulin resistance syndrome, which is associated with hyperinsulinemia, hypertension, hyperlipidemia, type 2 diabetes mellitus, and an increased risk of atherosclerotic cardiovascular disease. The present study was done to assess the effect of Gymnema sylvestre extract (GSE) in the high fat diet (HFD)-induced cellular obesity and cardiac damage in Wistar rats.

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