Open AccessDisseminated histoplasmosis with conjunctival involvement in an immunocompromised patient
Author(s) -
Arun Shirali,
Jyoti R. Kini,
Anjith Vupputuri,
Maria Kuruvila,
Venkatraya M Prabhu
Publication year - 2010
Publication title -
indian journal of sexually transmitted diseases
Language(s) - English
Resource type - Journals
eISSN - 1998-3816
pISSN - 0253-7184
DOI - 10.4103/0253-7184.68999
Subject(s) - medicine , histoplasmosis , nodule (geology) , histology , pathology , dermatology , bone marrow , paleontology , biology
We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule showed numerous intracellular Periodic Acid Schiff-positive rounded yeast cells within macrophages. Bone marrow aspirate confirmed disseminated histoplasmosis. The patient showed dramatic response after starting treatment with Amphotercin B.