Open AccessPrevalence and clinical presentation ofcryptococcal meningitisamong HIV seropositive patients
Author(s) -
VP Baradkar,
M Mathur,
Anuradha De,
S Kumar,
M Rathi
Publication year - 2009
Publication title -
indian journal of sexually transmitted diseases
Language(s) - English
Resource type - Journals
eISSN - 1998-3816
pISSN - 0253-7184
DOI - 10.4103/0253-7184.55474
Subject(s) - medicine , meningitis , cryptococcosis , cryptococcal meningitis , amphotericin b , gram staining , agar , mycosis , antifungal , human immunodeficiency virus (hiv) , immunology , surgery , viral disease , dermatology , antibiotics , microbiology and biotechnology , biology , bacteria , genetics
A total of 573 HIV seropositive and clinically suspected cases of Cryptococcal meningitis were included in the study, from January 2006 to January 2007. CSF samples were processed by negative staining with 10% Nigrosin, cultured on Sabouraud's dextrose agar, biochemical tests, such as urease test and brownish growth in Niger seed agar. The prevalence of Cryptococcal meningitis was found to be 2.79%. The most common signs and symptoms were: fever (100%), headache (100%), altered sensorium (100%), and neck stiffness (90%). All the patients responded to intravenous Amphotericin B treatment.