Open AccessAnti-retroviral therapy's miracle in the treatment of Bowen's disease in a human immunodeficiency virus-positive patient: A rare case report
Author(s) -
Kannan Gopalan,
Seethalakshmi Ganga Vellaisamy,
Navakumar Manickam,
Razil Ahamed
Publication year - 2016
Publication title -
indian journal of sexually transmitted diseases
Language(s) - English
Resource type - Journals
eISSN - 1998-3816
pISSN - 0253-7184
DOI - 10.4103/0253-7184.192123
Subject(s) - medicine , miracle , human immunodeficiency virus (hiv) , virology , antiretroviral therapy , antiretroviral medication , disease , severe combined immunodeficiency , immunodeficiency , rare disease , dermatology , immunology , viral load , immune system , gene , biology , genetics , political science , law
Bowen's disease (BD) is a form of squamous cell carcinoma in situ often associated with human papillomavirus. Co-infection with human immunodeficiency virus (HIV) is associated with a greater risk of malignancy. We describe a case of BD in a 52-year-old unmarried HIV-positive male who presented with extensive skin lesions of 1-year duration. Histopathology was suggestive of BD. He had been tried with topical imiquimod cream and cryo-therapy for 6 months. We observed no response for these above therapies. He was started on with anti-retroviral therapy (ART) as his CD4 count was 253 cells/mm 3 . The entire cutaneous lesions completely disappeared within 6 months of ART, which was an interesting incidence.