Open AccessHypokalemic paralysis secondary to tenofovir induced fanconi syndrome
Author(s) -
Vishal V Ramteke,
Rushi Deshpande,
O. P. Srivastava,
Adinath Wagh
Publication year - 2015
Publication title -
indian journal of sexually transmitted diseases
Language(s) - English
Resource type - Journals
eISSN - 1998-3816
pISSN - 0253-7184
DOI - 10.4103/0253-7184.167176
Subject(s) - hypophosphatemia , hypokalemia , medicine , fanconi syndrome , tenofovir , complication , paralysis , tubulopathy , pediatrics , proteinuria , hypokalemic periodic paralysis , surgery , human immunodeficiency virus (hiv) , virology , kidney
Tenofovir induced fanconi syndrome (FS) presenting as hypokalemic paralysis is an extremely rare complication in patients on anti-retroviral therapy. We report a 50-year-old male with acquired immunodeficiency syndrome on tenofovir-based anti-retroviral therapy who presented with acute onset quadriparesis. On evaluation, he was found to have hypokalemia with hypophosphatemia, glucosuria and proteinuria suggesting FS. He regained normal power in limbs over next 12 h following correction of hypokalemia. Ours would be the second reported case in India.