Open AccessNeurocognitive Impairments in Unaffected First-degree Relatives of Schizophrenia
Author(s) -
Virupaksha Shanmugam Harave,
Venkataram Shivakumar,
Sunil V. Kalmady,
Janardhanan C. Narayanaswamy,
Shivarama Varambally,
Ganesan Venkatasubramanian
Publication year - 2017
Publication title -
indian journal of psychological medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 24
eISSN - 0975-1564
pISSN - 0253-7176
DOI - 10.4103/0253-7176.207335
Subject(s) - endophenotype , neurocognitive , schizophrenia (object oriented programming) , psychology , first degree relatives , memory span , executive functions , cognition , audiology , working memory , cognitive flexibility , psychosis , clinical psychology , psychiatry , medicine , family history
Neurocognitive impairments of attention and executive functioning are trait abnormalities in schizophrenia, and these are considered to be endophenotypes. These deficits have been convincingly linked to prefrontal cortical functioning. In this study, we examined the cognitive performance in the domains of attention and executive functioning among first-degree relatives of Indian people with schizophrenia (high-risk [HR] patients) compared to healthy controls (HC).