Open AccessTeratogenicity with Olanzapine
Author(s) -
Sathya Prakash,
Rakesh Kumar Chadda
Publication year - 2014
Publication title -
indian journal of psychological medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 24
eISSN - 0975-1564
pISSN - 0253-7176
DOI - 10.4103/0253-7176.127266
Subject(s) - olanzapine , pregnancy , microcephaly , medicine , clinical practice , drug , antipsychotic , atypical antipsychotic , antipsychotic drug , psychiatry , pediatrics , schizophrenia (object oriented programming) , family medicine , biology , genetics
Olanzapine, a 2(nd) generation antipsychotic, is in use in the clinical practice for nearly a decade and a half now. It is classified as a category C drug with very few reports of its toxic effects on the fetus. In general, the risk benefit analysis warrants its use in pregnancy. We report a case of microcephaly and anopthalmos associated with the use of olanzapine in pregnancy. Although a causal role cannot be unequivocally proven, it calls for larger studies to explore this issue.