Open AccessApolipoprotein E gene polymorphism and total serum cholesterol level in Iranian population
Author(s) -
Javad Tavkoli Bazzaz,
Mohammad Reza Nazari,
Habibollah Nazem,
Parvin Amiri,
Hossein Fakhrzadeh,
Ramin Heshmat,
Sepideh Abbaszadeh,
Mahsa M. Amoli
Publication year - 2010
Publication title -
journal of postgraduate medicine/journal of postgraduate medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 52
eISSN - 0972-2823
pISSN - 0022-3859
DOI - 10.4103/0022-3859.68629
Subject(s) - apolipoprotein b , polymorphism (computer science) , total cholesterol , genetics , cholesterol , apolipoprotein e , gene , population , biology , medicine , endocrinology , allele , environmental health , disease
Apolipoprotein E (APOE) is known as a major regulator of blood lipid levels in humans. A number of APOE gene allelic variants have been reported including E2, E3 and E4. Recent studies suggested a role for APOE in obesity and increased Body Mass Index (BMI) and plasma lipid levels in obese children.