Open AccessNeurotoxoplasmosis mimicking intracranial tuberculoma
Author(s) -
Vikram Doraiswamy,
R K Vaswani,
K.R. Lahiri,
SS Kondekar
Publication year - 2010
Publication title -
journal of postgraduate medicine/journal of postgraduate medicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 52
eISSN - 0972-2823
pISSN - 0022-3859
DOI - 10.4103/0022-3859.62432
Subject(s) - medicine , tuberculoma , radiology , lesion , magnetic resonance imaging , clinical trial , tuberculosis , surgery , pathology
Neurotoxoplasmosis is a major cause of morbidity and mortality, especially in immunocompromised patients. Definitive diagnosis is invasive and difficult thereby requiring a therapeutic trial. We herein report a case of an 11-year-old boy who presented with a tuberculoma on computerized tomography (CT) brain and did not show any clinical improvement on anti-tuberculous drugs. Subsequently, reviewing the CT scans and with supportive serology, a diagnosis of neurotoxoplasmosis was considered. A trial of antitoxoplasmosis therapy was given to which the child fully responded in two weeks. Three weeks later, his magnetic resonance imaging showed complete resolution of the lesion. This report provides an insight into the significance of therapeutic trial in neurotoxoplasmosis.