Open AccessPulmonary miliary papillary/micropapillary adenocarcinoma manifesting as carcinomatous encephalitis
Author(s) -
Pradeep Vaideeswar,
S. S. Nayak,
Abhinay Verma,
NA Goel
Publication year - 2017
Publication title -
journal of postgraduate medicine/journal of postgraduate medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 52
eISSN - 0972-2823
pISSN - 0022-3859
DOI - 10.4103/0022-3859.201410
Subject(s) - medicine , pathology , anaplastic lymphoma kinase , papillary adenocarcinoma , adenocarcinoma , encephalitis , lymphoma , lung , autopsy , lung cancer , cancer , immunology , virus , malignant pleural effusion
The histological pattern and the associated molecular aberrations have an important bearing in the prognosis of pulmonary adenocarcinomas. Papillary and micropapillary growth patterns with mutations in epidermal growth factor receptor and anaplastic large-cell lymphoma kinase rearrangements have an aggressive clinical course. We report one such cancer in a 49-year-old woman, where it assumed a miliary pattern in the lungs, and the patient presented with neurological symptoms related to carcinomatous encephalitis, an infrequent metastatic manifestation.