Open AccessHemophagocytic lymphohistiocytosis secondary to Epstein Barr virus and Leishmania co-infection in a toddler
Author(s) -
Nerea DomínguezPinilla,
María Baro-Fernández,
González-Granado Li
Publication year - 2015
Publication title -
journal of postgraduate medicine/journal of postgraduate medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 52
eISSN - 0972-2823
pISSN - 0022-3859
DOI - 10.4103/0022-3859.147052
Subject(s) - medicine , hemophagocytic lymphohistiocytosis , toddler , immunology , leishmaniasis , virology , differential diagnosis , leishmania , pathology , psychology , developmental psychology , parasite hosting , disease , world wide web , computer science
This is the report of an EBV+Leishmanial co-infection. The patient developed hemophagocytic syndrome (HLH) and was treated with the standard HLH-2004 protocol. However, PCR in bone marrow discovered this secondary cause for HLH. In endemic countries, visceral leishmaniasis should be considered in the differential diagnosis even in EBV-related HLH, as chemotherapy toxicity may be avoided.