Hemophagocytic lymphohistiocytosis secondary to Epstein Barr virus and Leishmania co-infection in a toddler
Author(s) -
Nerea DomínguezPinilla,
M Baro-Fernández,
Luis Ignacio GonzálezGranado
Publication year - 2014
Publication title -
journal of postgraduate medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 52
eISSN - 0972-2823
pISSN - 0022-3859
DOI - 10.4103/0022-3859.147052
Subject(s) - medicine , toddler , hemophagocytic lymphohistiocytosis , virology , immunology , pediatrics , pathology , psychology , developmental psychology , disease
This is the report of an EBV+Leishmanial co-infection. The patient developed hemophagocytic syndrome (HLH) and was treated with the standard HLH-2004 protocol. However, PCR in bone marrow discovered this secondary cause for HLH. In endemic countries, visceral leishmaniasis should be considered in the differential diagnosis even in EBV-related HLH, as chemotherapy toxicity may be avoided.
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