Correlation of renin angiotensin system (RAS) candidate gene polymorphisms with response to Ramipril in patients with essential hypertension | Zendy

Sumeet Gupta | Zendy; I Chattopadhyaya | Zendy; BK Agrawal | Zendy; P. K. Sehajpal | Zendy; RK Goel | Zendy

Open Access

Correlation of renin angiotensin system (RAS) candidate gene polymorphisms with response to Ramipril in patients with essential hypertension

Author(s) -

Sumeet Gupta,

I Chattopadhyaya,

BK Agrawal,

P. K. Sehajpal,

RK Goel

Publication year - 2014

Publication title -

journal of postgraduate medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.405

H-Index - 52

eISSN - 0972-2823

pISSN - 0022-3859

DOI - 10.4103/0022-3859.147028

Subject(s) - ramipril , medicine , blood pressure , essential hypertension , angiotensin converting enzyme , renin–angiotensin system , endocrinology , pharmacology , ace inhibitor , gastroenterology

The renin-angiotensin system (RAS) is an important facet of blood pressure regulation physiology. Treatment of essential hypertension targets the RAS using Angiotensin Converting Enzyme Inhibitors (ACEIs). However, ACEIs are not uniformly effective and show inter-individual pharmacodynamic variations.

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