Open AccessGenetic polymorphisms associated with sulphadoxine-pyrimethamine drug resistance among Plasmodium falciparum field isolates in malaria endemic areas of Assam
Author(s) -
Jitendra Sharma,
Prafulla Dutta,
SA Khan,
Monika Soni,
Dipta Dey,
J Mahanta
Publication year - 2015
Publication title -
journal of postgraduate medicine/journal of postgraduate medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 52
eISSN - 0972-2823
pISSN - 0022-3859
DOI - 10.4103/0022-3859.147019
Subject(s) - dhps , plasmodium falciparum , malaria , haplotype , dihydropteroate synthase , pyrimethamine , drug resistance , sulfadoxine , genotype , biology , virology , locus (genetics) , genetics , gene , immunology
The emergence of antimalarial drug resistance malaria parasite is widespread in North eastern region of India. During January 2012-December 2013, we conducted active surveillance for detection of antifolate resistance-associated genetic polymorphisms in Plasmodium falciparum malaria parasite from different malaria endemic areas of Assam.