Open AccessEfficacy of pralidoxime in organophosphorus poisoning: Revisiting the controversy in Indian setting
Author(s) -
Indranil Banerjee,
SK Tripathi,
Aniruddha Roy
Publication year - 2014
Publication title -
journal of postgraduate medicine/journal of postgraduate medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 52
eISSN - 0972-2823
pISSN - 0022-3859
DOI - 10.4103/0022-3859.128803
Subject(s) - pralidoxime , medicine , atropine , randomized controlled trial , anesthesia , clinical trial , surgery , biochemistry , chemistry , acetylcholinesterase , enzyme
Poisoning with organophosphorus (OP) compounds constitutes a global public health problem. Standard treatment of OP poisoning involves use of atropine and pralidoxime. While efficacy of atropine is well-established, clinical experience with pralidoxime in management of OP poisoning is controversial.