Open AccessImmature teratoma of the nose and paranasal sinuses masquerading as bilateral nasal polyposis: A unique presentation
Author(s) -
Shilpi Aggarwal,
Amit Keshri,
Preeti Agarwal
Publication year - 2013
Publication title -
journal of postgraduate medicine/journal of postgraduate medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 52
eISSN - 0972-2823
pISSN - 0022-3859
DOI - 10.4103/0022-3859.113844
Subject(s) - teratoma , medicine , endoderm , ectoderm , germ layer , presentation (obstetrics) , pathology , nose , paranasal sinuses , differential diagnosis , mesoderm , histogenesis , germ cell tumors , anatomy , biology , surgery , embryogenesis , cellular differentiation , embryonic stem cell , embryo , immunohistochemistry , biochemistry , gene , microbiology and biotechnology , chemotherapy , induced pluripotent stem cell
Teratomas are tumors of multipotent cells derived from all three germ cell layers and recapitulate normal organogenesis. Teratomas are hypothesized to arise by misplacement of multipotent germ cells. Teratoma is usually developmental and sometimes congenital neoplasm which displays both solid and cystic components with gross and microscopic differentiation into a wide variety of tissues representative of all three germ layers--ectoderm, mesoderm and endoderm. We are describing a case which was initially diagnosed as bilateral nasal polyposis clinically but histopathology report came out to be immature teratoma. This case is being reported to make aware all ENT surgeons of such unique presentation of sinonasal teratomas as such presentation of these tumors has not been reported in literature previously, and hence teratomas should be considered in the differential diagnosis of nasal polyposis in future.