Open AccessAntidepressant-induced mania in obsessive compulsive disorder
Author(s) -
Johann Philip,
R Janaki
Publication year - 2012
Publication title -
indian journal of psychiatry/indian journal of psychiatry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.485
H-Index - 34
eISSN - 1998-3794
pISSN - 0019-5545
DOI - 10.4103/0019-5545.99543
Subject(s) - mania , olanzapine , antidepressant , psychiatry , depression (economics) , psychology , obsessive compulsive , bipolar disorder , reuptake inhibitor , sertraline , medicine , schizophrenia (object oriented programming) , lithium (medication) , anxiety , economics , macroeconomics
Serotonin-reuptake inhibitors have come forth to become the mainstay of treatment in obsessive compulsive disorder (OCD), predominantly as a result of evidence from clinical psychopharmacological response studies. Comorbid psychiatric disorders frequent OCD patients, most often depression. Although selective serotonin reuptake inhibitors are effective in the treatment of both OCD and depressive disorder, all antidepressants are associated with treatment-emergent affective switch. We present a 48-year-old patient with OCD, on antidepressants, initially for OCD and later for depression as well. She switched to mania after 20 years of treatment, which responded to olanzapine and divalproex sodium.